about zavzpret

What is zavzpret tm
(zavegepant)?

ZAVZPRET is the first and only CGRP receptor antagonist nasal spray. It is a prescription medicine used in adults for the acute treatment of migraine attacks with or without aura. ZAVZPRET was proven in clinical trials to deliver fast, effective treatment that is generally well tolerated.

ZAVZPRET was evaluated for the acute treatment of migraine attacks

In a study of 623 people taking ZAVZPRET vs 646 people taking placebo, people taking ZAVZPRET experienced the following:

ZAV_2_hours
  • At 2 hours, ZAVZPRET:
  • provided freedom from pain in 24% (n=147/623) of people taking ZAVZPRET vs 15% (n=96/646) taking the placebo
  • provided freedom from most bothersome symptom* in 40% (n=247/623) of people taking ZAVZPRET vs 31% (n=201/646) taking the placebo
ZAVZPRET™ (zavegepant) Nasal Cavity Illustration

Why a nasal spray?

The medication is rapidly absorbed in the nasal cavity, directly entering the bloodstream, so it can start to work quickly.

One spray to rapidly reclaim your moments

Nasal Spray Icon

ONE SPRAY

in one nostril for rapid absorption

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Rapid freedom

from pain at 2 hours

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RAPID FREEDOM

from most bothersome symptom (MBS) at 2 hours

What about possible side effects?

ZAVZPRET may cause serious side effects. Allergic reactions, including hives and swelling of the face, can occur after you use ZAVZPRET. Call your healthcare provider or get emergency help if you have swelling of the face, mouth, tongue, or throat or trouble breathing.


In clinical studies, the most common side effects were unusual taste, nausea, nasal discomfort, and vomiting. Eighteen percent of people temporarily experienced unusual taste after using ZAVZPRET.

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ZAVZPRET was not associated with sedation or fatigue in clinical trials

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Most side effects in clinical trials were mild or moderate

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Tell your healthcare provider if you experience any bothersome side effects

Think ZAVZPRET might be right for you?

Think ZAVZPRET might be right for you?

If you’re thinking this...

A nasal spray could be right for me, but I’m worried about potential side effects.

...ask your healthcare provider this

I've heard there is a non-oral CGRP receptor antagonist that might be able to help with my acute migraine attacks. Can you explain the potential side effects?

If you’re thinking this...

A nasal spray could be right
for me, but I’m worried about
potential side effects.

I don’t want to plan my life around
migraine. I want to feel like I have
what I need, the moment it crashes in.

Despite all that I do, I still
experience migraine attacks.
It feels like they often hit at
the worst possible moment.

...ask your healthcare provider this

I've heard there is a non-oral CGRP
receptor antagonist that might be able
to help with my acute migraine attacks Can you explain the potential side effects?

Is there a nasal spray I could take, in the moment, for migraine relief?

I still experience migraine attacks.
Is there anything I can turn to in
those moments?

Talk to your healthcare provider about what you're experiencing. In the meantime, see how easy it can be to get your prescription.

GETTING ZAVZPRETButton arrow

WHAT IS ZAVZPRET?

ZAVZPRET™ (zavegepant) nasal spray is a prescription medicine used in adults for the acute treatment of migraine attacks with or without aura.

ZAVZPRET is not used to prevent migraine attacks. It is not known if ZAVZPRET is safe and effective in children.

Please see the full Prescribing Information and Patient Information, including Instructions for Use.

IMPORTANT SAFETY INFORMATION AND APPROVED USE

Do not use ZAVZPRET if you are allergic to ZAVZPRET or its ingredients.

Before you use ZAVZPRET, tell your healthcare provider about all of your medical conditions, including if you:

  • have kidney problems
  • have liver problems
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

ZAVZPRET may cause serious side effects. Allergic reactions, including hives and swelling of the face can occur after you use ZAVZPRET. Call your healthcare provider or get emergency help if you have swelling of the face, mouth, tongue, or throat or trouble breathing.

The most common side effects of ZAVZPRET include unusual taste, nausea, nasal discomfort, and vomiting. These are not the only possible side effects
of ZAVZPRET. Tell your healthcare provider if you have any side effects.

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