ZAVZPRET is a prescription medicine used in adults for the acute treatment of migraine attacks with or without aura. It's a nasal spray proven to treat migraine pain fast.*
*Pain freedom was experienced in 2 hours, and some patients experienced pain relief in as little as 15 minutes.
ZAVZPRET is rapidly absorbed in the nasal cavity, directly entering the bloodstream so it can get to work fast on migraine. One spray could provide up to 48 hours of migraine freedom.
Freedom from pain at 2 hours† that lasted up to 48 hours‡
Freedom from most bothersome symptom at 2 hours† and back to normal function in just 30 minutes§
Pain relief in as little as 15 minutes in some patients‖
See additional details below.
provided freedom from pain in 24% (n=147/623) of people taking ZAVZPRET vs 15% (n=96/646) taking the placebo
provided freedom from most bothersome symptom (light sensitivity, sound sensitivity, or nausea) in 40% (n=247/623) of people taking ZAVZPRET vs 31% (n=201/646) taking the placebo
provided pain relief in 59% (n=366/623) of people taking ZAVZPRET vs 50% (n=321/646) taking the placebo
helped patients experience a return to normal function in 36% (n=204/570) of people taking ZAVZPRET vs 26% (n=152/593) taking the placebo
provided sustained pain freedom in 12% (n=77/623) of people taking ZAVZPRET vs 9% (n=56/646) taking the placebo
provided the ability to function normally in 11% (n=60/570) of people taking ZAVZPRET vs 6% (n=36/593) taking the placebo
provided pain relief in 16% (n=99/623) of people taking ZAVZPRET vs 8% (n=52/646) taking the placebo
In clinical studies, 18% of people temporarily experienced unusual taste after using ZAVZPRET. The most common side effects were unusual taste, nausea, nasal discomfort, and vomiting. Allergic reactions, including hives and swelling of the face, can occur after using ZAVZPRET. High blood pressure and a circulation problem called Raynaud's phenomenon may occur or worsen after taking ZAVZPRET. Call your healthcare provider or get emergency help if you have swelling of the face, mouth, tongue, or throat or trouble breathing.
ZAVZPRET was not associated with sedation or fatigue in clinical trials.
Most side effects in clinical trials were mild or moderate.
Tell your healthcare provider if you experience any bothersome side effects.
Real ZAVZPRET patient.
WHAT IS ZAVZPRET?
ZAVZPRET (zavegepant) nasal spray is a prescription medicine used in
adults for the acute treatment of migraine attacks with or without
aura.
ZAVZPRET is not used to prevent migraine attacks. It is not known if
ZAVZPRET is safe and effective in children.
Please click here for full Prescribing Information and Patient Information, including Instructions for Use.
IMPORTANT SAFETY INFORMATION
Do not use ZAVZPRET if you are allergic to ZAVZPRET or its ingredients.
Before you use ZAVZPRET, tell your healthcare provider (HCP) about all of your medical conditions, including if you
Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
ZAVZPRET may cause serious side effects, including:
Allergic reactions, including hives and swelling of the face, can occur after you use ZAVZPRET. Call your HCP or get emergency help if you have swelling of the face, mouth, tongue, or throat or trouble breathing.
High blood pressure can worsen or occur after you take ZAVZPRET. Contact your HCP if you have an increase in blood pressure.
A circulation problem called Raynaud's phenomenon can worsen or occur after you take ZAVZPRET. This can lead to your fingers or toes feeling numb, cool, or painful, or changing color from pale, to blue, to red. Contact your HCP if these symptoms occur.
The most common side effects of ZAVZPRET include unusual taste,
nausea, nasal discomfort, and vomiting. These are not the only
possible side effects
of ZAVZPRET. Tell your HCP if you have
any side effects.
You are encouraged to report adverse events related to Pfizer products by calling 1-800-438-1985 (U.S. only). If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/medwatch or call 1800FDA1088.
WHAT IS ZAVZPRET?
ZAVZPRET (zavegepant) nasal spray is a prescription medicine used in adults for the acute treatment of migraine attacks with or without aura.
ZAVZPRET is not used to prevent migraine attacks. It is not known if ZAVZPRET is safe and effective in children.
Please click here for full Prescribing Information and Patient Information, including Instructions for Use.
IMPORTANT SAFETY INFORMATION
Do not use ZAVZPRET if you are allergic to ZAVZPRET or its ingredients.
Before you use ZAVZPRET, tell your healthcare provider (HCP) about all of your medical conditions, including if you
Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
ZAVZPRET may cause serious side effects, including:
Allergic reactions, including hives and swelling of the face, can occur after you use ZAVZPRET. Call your HCP or get emergency help if you have swelling of the face, mouth, tongue, or throat or trouble breathing.
High blood pressure can worsen or occur after you take ZAVZPRET. Contact your HCP if you have an increase in blood pressure.
A circulation problem called Raynaud's phenomenon can worsen or occur after you take ZAVZPRET. This can lead to your fingers or toes feeling numb, cool, or painful, or changing color from pale, to blue, to red. Contact your HCP if these symptoms occur.
The most common side effects of ZAVZPRET include unusual taste,
nausea, nasal discomfort, and vomiting. These are not the only
possible side effects
of ZAVZPRET. Tell your HCP if you have
any side effects.
You are encouraged to report adverse events related to Pfizer products by calling 1-800-438-1985 (U.S. only). If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/medwatch or call 1800FDA1088.
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