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For the acute treatment of migraine attacks with or without aura in adults
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Burton Buffaloe standing in front of a desk. Real ZAVZPRET® patient.
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Burton Buffaloe standing in front of a desk. Real ZAVZPRET® patient.
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Using ZAVZPRET
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“I carry ZAVZPRET® (zavegepant) with me so I might not have to miss a moment.”

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Burton Buffaloe
Husband, father, and modern farmer
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Real ZAVZPRET patient
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Thumbnail of the "Tips for How to Use ZAVZPRET®" video.
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Tips for how to use ZAVZPRET

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Watch the video or explore the guide below to learn more.
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Prescribing Information

Patient Information

Instructions for Use
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Full instructions can be found in our Instructions for Use guide.
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Prepare

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  • Store ZAVZPRET at room temperature (68°F-77°F)*
  • Remove one package from carton and check expiration date (throw away if expired)
  • Peel open package to remove device and check its expiration date (throw away if expired)

*The device should be stored at room temperature between 68°F to 77°F (20°C to 25°C). Do not freeze. Keep the device in the sealed blister package until time of use. Keep ZAVZPRET and all medicines out of reach of children.

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Spray

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  • Gently blow your nose
  • Grip the device with your thumb on the bottom of the plunger and 2 fingers on either side of the nozzle (do not press yet)
  • Close one nostril with your free hand and breathe through your mouth
  • Keep your head upright and level
  • Insert nozzle into your open nostril and slowly breathe in through your nose as you firmly press the plunger up with your thumb to release the spray
  • Do not let the nozzle come out when pressing the plunger
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Remove and dispose

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  • Remove device and keep head level for 20 seconds
  • Remove device from your nostril. Gently breathe in through your nose and out through your mouth for 10-20 seconds
  • Throw away device
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ZAVZPRET® (zavegepant) nasal spray packaging and device among miscellaneous items.
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ZAVZPRET® (zavegepant) nasal spray packaging and device among miscellaneous items.
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Don’t forget to add ZAVZPRET

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Eye masks, cold caps, and blackout curtains
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  • One spray, in one nostril, in one pocket-sized package
  • ZAVZPRET can go to work on migraine pain in as little as 15 minutes and can provide freedom from pain and most bothersome symptom in 2 hours
  • Can get people with migraine back to normal function in just 30 minutes§ so they can get back to what matters
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In clinical studies, 16% of patients taking ZAVZPRET experienced pain relief at 15 minutes vs 8% taking placebo.

In clinical studies, 40% of people taking ZAVZPRET had freedom from most bothersome symptom at 2 hours vs 31% taking placebo.

§In clinical studies, 11% of patients taking ZAVZPRET were able to function normally at 30 minutes vs 6% taking placebo.

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A hand holding ZAVZPRET® (zavegepant) nasal spray surrounded by a savings card, an alert icon, and a shipping icon.
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A hand holding ZAVZPRET® (zavegepant) nasal spray surrounded by a savings card, an alert icon, and a shipping icon.
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Eligible patients could try ZAVZPRET for less

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Save on ZAVZPRET
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